个人基本信息
姓名：刘薇
性别：女
职称：校聘副教授、青年英才
邮编：450002
通讯地址：河南省郑州市金水区文化路95号 3200威尼斯vip(官方VIP认证)-最新App Store
E-mail：liuv@henau.edu.cn
性别：女
职称：校聘副教授、青年英才
邮编：450002
通讯地址：河南省郑州市金水区文化路95号 3200威尼斯vip(官方VIP认证)-最新App Store
E-mail：liuv@henau.edu.cn
个人简介
2017.09-至今 河南农业大学 动物学系 讲师；
2013-09至2017-07, 中国科3200威尼斯vip大学, 微生物研究所, 博士
2010-09至2013-07, 天津科技大学, 食品工程与生物技术3200威尼斯vip, 硕士
2006-09至2010-07, 内蒙古科技大学, 3200威尼斯vip, 学士
2013-09至2017-07, 中国科3200威尼斯vip大学, 微生物研究所, 博士
2010-09至2013-07, 天津科技大学, 食品工程与生物技术3200威尼斯vip, 硕士
2006-09至2010-07, 内蒙古科技大学, 3200威尼斯vip, 学士
教授课程
本科生：《发育生物学》、《细胞工程》
研究生：《发育生物学》
研究生：《发育生物学》
主要研究领域
宿主抗病毒的天然免疫信号通路的研究；动物病毒与宿主相互作用的机制研究
近五年发表论著
1.Wei Liu*, Zhenling Ma, Yaru Wu, Cui Yuan, Yanyan Zhang, Zeyang Liang, Yu Yang, Wenwen Zhang，Pengtao Jiao*. MST4 negatively regulates type I interferons production via targeting MAVS-mediated pathway. Cell Communication and Signaling, 2022,20:103. （IF= 7.525）
2.Yaru Wu, Zhenling Ma, Yanyan Zhang, Min Zhang, Wenwen Zhang, Menghao Zhang, Xixi Shi, Wenqing Li，Wei Liu*. Cyclophilin A regulates the apoptosis of A549 cells by stabilizing Twist1 protein. Journal of Cell Science, 2022, 135, jcs259018. （IF= 5. 235）
3.Zhenling Ma, Wenwen Zhang, Wenhui Fan, Yaru Wu, Menghao Zhang, Jun Xu，Wenqing Li, Lei Sun, Wenjun Liu, Wei Liu*. Forkhead box O1-mediated ubiquitination suppresses RIG-I-mediated antiviral immune responses, International Immunopharmacology, 2021, 90:107152. （IF= 5.714）
4.Wenwen Zhang, Zhenling Ma, Yaru Wu, Xixi Shi, Yanyan Zhang Min Zhang, Menghao Zhang, Lei Wang, Wei Liu*. SARS-CoV-2 3C-like protease antagonizes interferon-beta production by facilitating the degradation of IRF3. Cytokine, 2021, 148x155697. （IF= 3.926）
5.Zhenling Ma, Wenwen Zhang, Yaru Wu, Menghao Zhang, Lei Wang, Yihan Wang, Yi Wang, Wei Liu*. Cyclophilin A inhibits A549 cell oxidative stress and apoptosis by modulating the PI3K/Akt/mTOR signaling pathway, Bioscience Reports, 2021, 29; 41(1): BSR20203219. （IF= 3.976）
6.Wei Liu, Lei Wang, Jiajia Zhang, Liuhui Qiao, Yiqing Liu, Xinke Yang, Jinghua Zhang, Wenming Zheng, Zhenling Ma. Purification of recombinant human chemokine CCL2 in E. coli and its function in ovarian cancer, 3 Biotech, 2021, 11(1): 8. （IF= 2.893）
7.Wei Liu, Jing Li, Weinan Zheng, Yingli Shang, Zhendong Zhao, Shanshan Wang, Yuhai Bi, Shuang Zhang, Chongfeng Xu, Ziyuan Duan, Lianfeng Zhang, Yue L Wang, Zhengfan Jiang, Wenjun Liu, Lei Sun. Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses, Elife, 2017, 6: e24425. （IF:8.303）
8.Wei Liu, Xiangyi Lu, Guangyang He, Xiang Gao, Maonian Xu, Jingkai Zhang, Meiling L, Lifeng Wang, Zhenjing Li, Likui Wang, Cheng Luo. Protective Roles of Gadd45 and MDM2 in Blueberry Anthocyanins Mediated DNA Repair of Fragmented and Non-Fragmented DNA Damage in UV-Irradiated HepG2 Cells, International Journal of Molecular Sciences, 2013, 14:21447-21462.
9.Wei Liu, Xiangyi Lu, Guangyang He, Xiang Gao, Mengxian Li, Junhua Wu, Zhenjing Li, Jihui Wu, Juncheng Wang, Cheng Luo. Cytosolic protection against ultraviolet induced DNA damage by blueberry anthocyanins and anthocyanidins in hepatocarcinoma HepG2 cells. Biotechnology Letters, 2013, 35 (4): 491-498.
10.岳岩磊, 张稳稳, 张梦豪, 刘薇*. Cyclophilin A 在病毒感染中的作用研究进展. 中国免疫学杂志, 2021, 37: 1012-1021.
11.马振玲, 王雷,乔柳惠 , 刘薇*. 小鼠 CCL2 蛋白原核表达及纯化分析.生物学杂志，2021,38（6）: 20-24.
12.张稳稳，岳岩磊，马振玲，姚文，杨国庆，刘薇*. FoxO1 在病毒感染和炎症发生中的作用. 病毒学报，2021，37（3）: 726-731.
13.刘薇，王红霞，王立魁，苏丽丽，罗成. COX-2/Nrf2/ARE信号通路与体内外的抗炎、抗氧化作用机理. 生命科学,2011, 23 (10): 1027-1033.
2.Yaru Wu, Zhenling Ma, Yanyan Zhang, Min Zhang, Wenwen Zhang, Menghao Zhang, Xixi Shi, Wenqing Li，Wei Liu*. Cyclophilin A regulates the apoptosis of A549 cells by stabilizing Twist1 protein. Journal of Cell Science, 2022, 135, jcs259018. （IF= 5. 235）
3.Zhenling Ma, Wenwen Zhang, Wenhui Fan, Yaru Wu, Menghao Zhang, Jun Xu，Wenqing Li, Lei Sun, Wenjun Liu, Wei Liu*. Forkhead box O1-mediated ubiquitination suppresses RIG-I-mediated antiviral immune responses, International Immunopharmacology, 2021, 90:107152. （IF= 5.714）
4.Wenwen Zhang, Zhenling Ma, Yaru Wu, Xixi Shi, Yanyan Zhang Min Zhang, Menghao Zhang, Lei Wang, Wei Liu*. SARS-CoV-2 3C-like protease antagonizes interferon-beta production by facilitating the degradation of IRF3. Cytokine, 2021, 148x155697. （IF= 3.926）
5.Zhenling Ma, Wenwen Zhang, Yaru Wu, Menghao Zhang, Lei Wang, Yihan Wang, Yi Wang, Wei Liu*. Cyclophilin A inhibits A549 cell oxidative stress and apoptosis by modulating the PI3K/Akt/mTOR signaling pathway, Bioscience Reports, 2021, 29; 41(1): BSR20203219. （IF= 3.976）
6.Wei Liu, Lei Wang, Jiajia Zhang, Liuhui Qiao, Yiqing Liu, Xinke Yang, Jinghua Zhang, Wenming Zheng, Zhenling Ma. Purification of recombinant human chemokine CCL2 in E. coli and its function in ovarian cancer, 3 Biotech, 2021, 11(1): 8. （IF= 2.893）
7.Wei Liu, Jing Li, Weinan Zheng, Yingli Shang, Zhendong Zhao, Shanshan Wang, Yuhai Bi, Shuang Zhang, Chongfeng Xu, Ziyuan Duan, Lianfeng Zhang, Yue L Wang, Zhengfan Jiang, Wenjun Liu, Lei Sun. Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses, Elife, 2017, 6: e24425. （IF:8.303）
8.Wei Liu, Xiangyi Lu, Guangyang He, Xiang Gao, Maonian Xu, Jingkai Zhang, Meiling L, Lifeng Wang, Zhenjing Li, Likui Wang, Cheng Luo. Protective Roles of Gadd45 and MDM2 in Blueberry Anthocyanins Mediated DNA Repair of Fragmented and Non-Fragmented DNA Damage in UV-Irradiated HepG2 Cells, International Journal of Molecular Sciences, 2013, 14:21447-21462.
9.Wei Liu, Xiangyi Lu, Guangyang He, Xiang Gao, Mengxian Li, Junhua Wu, Zhenjing Li, Jihui Wu, Juncheng Wang, Cheng Luo. Cytosolic protection against ultraviolet induced DNA damage by blueberry anthocyanins and anthocyanidins in hepatocarcinoma HepG2 cells. Biotechnology Letters, 2013, 35 (4): 491-498.
10.岳岩磊, 张稳稳, 张梦豪, 刘薇*. Cyclophilin A 在病毒感染中的作用研究进展. 中国免疫学杂志, 2021, 37: 1012-1021.
11.马振玲, 王雷,乔柳惠 , 刘薇*. 小鼠 CCL2 蛋白原核表达及纯化分析.生物学杂志，2021,38（6）: 20-24.
12.张稳稳，岳岩磊，马振玲，姚文，杨国庆，刘薇*. FoxO1 在病毒感染和炎症发生中的作用. 病毒学报，2021，37（3）: 726-731.
13.刘薇，王红霞，王立魁，苏丽丽，罗成. COX-2/Nrf2/ARE信号通路与体内外的抗炎、抗氧化作用机理. 生命科学,2011, 23 (10): 1027-1033.
科研项目
1、亲环素A对NLRP3炎症小体介导IL-1β产生的调控机制，国家自然科学基金， 2019.1-2021.12，主持
2、CyclophilinA对TLR3介导的IFN产生的调控机制、河南农业大学青年英才项目， 2018.06-2023.6，主持
2、CyclophilinA对TLR3介导的IFN产生的调控机制、河南农业大学青年英才项目， 2018.06-2023.6，主持
